Oxandrolone is often used as a growth stimulant in the therapy of children (boys) lagging behind in physical development. A study in Italy showed that in such patients, oxandrolone is as effective as growth hormone preparations. A study by French scientists found that the substance is superior to growth hormone in the treatment of girls with Turner syndrome, one of the reasons for the delay in physical development. In obese individuals, oral administration of oxandrolone helped to reduce the mass of subcutaneous fat deposits in the abdominal region more effectively than testosterone enanthate or exercise.
The action of oxandrolone is to increase the amount of growth hormone produced in each release cycle, while the drug does not change the duration of the excretory cycles or half-lives of the hormone.
Only 2.5 mg of the substance positively alter the balance of nitrogen in the body. Doses taken by bodybuilders range from 0.125 mg to 2.5 mg per 1 kg of body weight. Studies do not confirm the increased effectiveness of doses exceeding 1.1 mg / kg, and European bodybuilding trainers are considered the optimal dose from 0.25 to 0.5 mg / kg. Many male bodybuilders report significant improvements in strength and recovery with 30 to 80 mg of oxandrolone per day. Women take about half the men’s dose.
Oxandrolone is used in many areas – in competitive bodybuilding, in sports, where athletes are divided into weight categories, cycling and in power sports. In the field of strength training, Oxandrolone is recognized as the most effective drug for increasing strength among those dosed in milligrams.
It is considered to be the best stimulator for producing creatine phosphate in muscle tissue, but this argument has no scientific confirmation.
A low level of androgenic effects when taking the drug made it popular among female athletes, in particular among female bodybuilders.
Oxandrolone has almost no toxic effects on the liver, even with high doses of 80 mg per day. He was prescribed even to patients suffering from cirrhosis of the liver.
Oxandrolone does not inhibit the functioning of the system of the sex glands and the pituitary gland in men. There is no evidence that he suppresses the production of sperm and testosterone, so osandrolone is often taken between courses. Many bodybuilders were able to give up steroids by switching to taking 30 mg of oxandrolone per day and gradually lowering the dose by 2.5 mg every five days until the body’s natural production of testosterone was restored.
Bodybuilders consider it an excellent preparation for preparation for competitions. Athletes report that, in comparison with other steroids, the results achieved with taking oxandrolone results remain much longer.
This is one of the small number of anabolic drugs that does not lead to premature closure of the otolithous epiphysis in children.
Since oxandrolone does not cause the formation of estrogens (the so-called “aromatization” of steroids), there is no need to take with it tamoxifen, proviron or citadren.
The drug has more negative effects on blood lipids than is usually indicated in the scientific literature.
In women, taking doses exceeding 15 mg per day, the drug can cause hair growth on the face, lowering the voice, hypertrophy of the clitoris and skin rashes.
A very small percentage of those taking oxandrolone reported gastroenteric disorders, such as a feeling of heaviness in the stomach, lack of appetite, nausea and diarrhea.